guest OS to host system I need to press "Ctrl" key (my Host key is Ctrl) .This is because seamless mouse pointer integration is not enable. This is painful and takes time to jump between guest OS and host system. After reading some forums post and web articles I have come across with a solution.In this method there will be one mouse pointer and pressing the Host key is no longer required to "free" the mouse from being captured by the guest OS and vice-versa. Following steps guide how to enable seamless mouse support on linux based guest system.
 install gcc and kernel-develinstall the GNU C compiler and the kernel development packages using
#yum install gcc
#yum install kernel-devel
 Reboot guest systemReboot your guest system in order to activate the updates.
Install Guest AdditionsClick "Devices" --> "Install Guest Additions"
 Follow the installation wizard
you will get window similar to below and click "OK" , you may need provide authentication
 It will be prompted with terminal window similar to following, Press Return and